The Mississipian culture, which will later greatly influence many Native American tribes (i.e., the Chickasaw), is formed. This was the last culture that would depend on mound-building in North America.
During this period, the Adena and Hopewell cultures are established along Northeastern and Midwestern U.S rivers. Trade becomes a major part of these cultures. These cultures will have a great influence on the Shawnee tribe and their trading system with the French.
The Arrival of Hernando de Soto
1500 - 1542
Hernando de Soto begins to explore the area for gold and discovers the Native Americans already residing there (all the Native American tribes present).
The Chickasaw and the Creek Indian tribes participate in the Creek War or, also known as, the Red Stick War. The Creek Indians were defeated by Andrew Jackson at the Horseshoe Bend where 750 Creeks were drowned or killed along with 201 whites.