DNA Timeline-Foor

Main

Gregor Mendel

1851

Did research on heredity/gentics on pea plants

Friedrich Miescher

1868

the first researcher to isolate and identify nucleic acid.

Frederick Griffith

1928

Studied whether or not "R" cells and "S" cells treated differently would infect a mouse, discovered transformation.

George Beadle, Edward Tatum

1931

Known for gene regulation of biochemical events within cells.
showed that genes control individual steps in metabolism

Oswald Avery

1940

Tested whether or not the transforming agent in Griffith's experiment was protein, RNA, or DNA

Erwin Chargaff

1949

Observed that the percentages of adenine equals the percentage of thymine. The percentage of cytosine equals the percentage of Guanine. Now called base pairs

James Watson, Francis Crick, Rosalind Franklin, Maurice Wilkins

1950 - 1959

Watson and Crick created the Double helix model, with help of the pictures by Franklin and Wilkins.

Mahlon Hoagland

1950

Discorver tRNA

Martha Chase, Alfred Hershey

1952

Tested whether or not DNA or protein was the hereditary material viruses transfer when viruses enter a bacterium.

Matthew Meselson, Frank Stahl

1957

Showed how DNA replicated

Marshall Nirenberg

1959

"broke" the genetic code

Sydney Brenner

1960

Brenner created the first computer matrix analysis of nucleic acids. Discovered frameshift mutations

Nobel Peace prize awarded to Watson, Crick and Wilkins

1962

Franklin was already dead, but is honored in the Cambridge Institute.

Howard Temin

1970

discovered reverse transcriptase

David Baltimore

1981

Studied recombinant DNA and the genome of poliovirus.

Paul Zamercnik

1989

Antisense therapy- genetic mutations