Alexis Carrel developed new ways to suture blood vessels http://www.nobelprize.org/nobel_prizes/medicine/laureates/1912/carrel.jpg
A mechanical heart was developed that could pump blood
Frank Mann transplanted a heart into the neck of the dog and kept it alive for 8 days
Vladimir Demikhov transplanted hearts into the chest cavities of dogs and they lived
Sheep, Baboon, and Chimp hearts were transplanted into adults
James Hardy tried transplanting a chimp heart into a 68-year-old man, but the heart was too small and failed days after
Dr.Adrian Kantrowitz and his brother, an engineer, together were responsible for the development and 1st successful clinical use of the modern-day intra-aortic balloon pump.
The first successful heart was transplanted into a 55-year-old man by Christiaan Barnard http://www.capegateway.gov.za/image/2005/2/washkansky.jpg
Dr.Kantrowitz and associates used an anencephalic donor heart to replace the heart of a 3-week old patient with type IA tricuspid atresia and atrial communication, the baby died.
100 heart transplants were performed but none survived long
Cyclosporine A helped T-cells stop to avoid rejection of the heart implant.
The Stanford group formulated a new technology- percutaneous transvenous endomyocardial biopsy, improved overall effectiveness of open heart surgery.
John McCaftery held the world record for longest surviving heart transplant
World's first successful pediatric transplant performed on a 4 year old boy