First chemical tests to measure the presence of glucose in the urine are developed
Substance linked to diabetes discovered in the Pancreas
A german medical student, Langerhans, discovers the the pancreas is responsible for secreting two times of cells, one of them being the hormone Insulin.
Bernard's Liver Theory Disproved
Scientist Von Mering disproved the theory that removing the pancreas caused Diabetes.
Pancreatic fluid first used to treat Diabetes
Zuelzer extracts insulin from the Pancreas and injects it into five patients with diabetes. Glucose in the urine is reduced by the treatment but there were many negative side effects.
Benedict's Solution Invented
Benedict creates a new method, Benedict's Solution, to more effectively measure the amount of glucose in urine.
"Studies Concerning Glycosuria and Diabetes" released
Allen's book, "Studies Concerning Glycosuria and Diabetes" introduces a change in diabetes therapy from this point in time
Official Discovery of Insulin
Took place in 1921 in Canada by Fredrick Banting, an unsuccessful orthopaedic surgeon, who after reading about the association between the pancreas and diabetes became convinced that he could find the antidiabetic substance.
First human to receive insulin
On January 11, 1922, a 14-year-old boy became the first human patient to receive insulin made by Banting and Best.
Commercial Production of Insulin
Eli Lilly begins commercial production of insulin.
Home testing for glucose in urine introduced
Home testing for sugar in urine is introduced. This simple color reactivity test allowed for closer monitoring of diabetes at home.
Protamine Zinc insulin
1936, protamine zinc insulin was introduced. This was longer lasting and allowed for more flexibility.