the Court held that the commerce clause gave Congress authority to prohibit the local cultivation and use of marijuana, despite state law to the contrary. Stevens argued that the Court's precedent "firmly established" Congress' commerce clause power to regulate purely local activities that are part of a "class of activities" with a substantial effect on interstate commerce.
Very important distinction of facial and as applied challenges. This is an as applied case.
Facial: Challenge to statute which plaintiff alleges that he legislation is always unconstitutional
As Applied: Challenge which alleges that particular application of a statute.
This case is distinguishable from lopez because all parts of this case is economical.