Untitled timeline

Main

Mendel's

1866

paper is published: units of inheritance in pairs; dominance and recessiveness; equal segregation; independent assortment. These ideas are not recognized for 34 year.
http://www.bio.davidson.edu/people/kahales/301Genetics/timeline.html

Friedrich Miescher

1869

DNA (first called "nuclein") as an acidic substance found in cell nuclei. The significance of DNA is not appreciated for over 70 years.
http://www.bio.davidson.edu/people/kahales/301Genetics/timeline.html

Sir Archibald Garrod

1902

1902 A human disease is first attributed to genetic causes ("inborn errors of metabolism").
http://www.bio.davidson.edu/people/kahales/301Genetics/timeline.html

TH Morgan

1911

shows the first example of chromosomal linkage in the X chromosome of Drosophila; EB Wilson shows that the gene for colour-blindness is on the X chromosome (first gene identified on a chromosome); Davenport founds the first US genetic clinic.
http://dorakmt.tripod.com/genetics/notes01.html

TH Morgan

1912

shows that genetic recombination does not take place in males in Drosophila and also discovers the first sex-linked lethal gene
http://dorakmt.tripod.com/genetics/notes01.html

Karl Ereky

1919

coins the term biotechnology (to mean production of beer, cheese, bread etc with the help of living organisms).
http://dorakmt.tripod.com/genetics/notes01.html

George Wells Beadle & Edward Lawrie

1941

Tatum proposes the one gene - one enzyme (polypeptide) concept.
http://dorakmt.tripod.com/genetics/notes01.html

Joseph Sambrook

1973

Led the team at Cold Spring Harbor Laboratory that refined DNA electrophoresis by using agarose gel and staining with ethidium bromide
http://www.accessexcellence.org/AE/AEPC/WWC/1994/geneticstln.php

Kary B. Mullis

1985

Published a paper describing the polymerase chain reaction (PCR), the most sensitive assay for DNA yet devised.
http://www.accessexcellence.org/AE/AEPC/WWC/1994/geneticstln.php

Francis Collins

1989

Lap-Chee Tsui Identified the gene coding for the cystic fibrosis transmembrane conductance regulator protein (CFTR) on chromosome 7 that, when mutant, causes cystic fibrosis.
http://www.accessexcellence.org/AE/AEPC/WWC/1994/geneticstln.php