Widespread famine and plague breaks out in north-eastern China
The plague reaches the trading city of Kaffa. The Genoan merchants return to Sicily spreading the disease.
The Genoan merchants travelled again to Constantinople Cyprus.
The plague reaches the French cities and the plague travels through water ( Rhine River )
The plague reaches Egypt and the Whole Islamic is affected by the plague.
The plague has spread all around the Mediterranean Sea
The Black Death kills over 35 million people