Rudolf Emmerich and Oscar Low are the first doctors to make an effective medication that they called pyocyanese. It was the first antibiotic to be used in hospitals. However, the medication often did not work.
Sir Alexander Fleming observed that the bacterium Staphylococcus could be destroyed by the mold Penicillin.
Protonsil was discovered by German chemist Gerhard Domagk.
The manufacturing process for Penicillin was invented by Howard Florey and Ernst Chain. Penicillin could now be sold as a drug.
American microbiologist Selman Waksman made the drug streptomycin from soil bacteria, the first of a new class of drugs called aminoglycosides. Streptomycin could treat diseases like tuberculosis, however, the side effects were often too severe.
Fleming, Florey, and Chain shared the 1945 Nobel Prize for medicine for their work on penicillin.
Aminoglycosides are a group of antibiotics that are used to treat certain bacterial infections. This group of antibiotics includes at least eight drugs: amikacin, gentamicin, kanamycin, neomycin, netilmicin, paromomycin, streptomycin, and tobramycin.
Tetracycline is used to treat bacterial infections, including pneumonia and other respiratory tract infections.
Farmers start to add low levels of antibiotics to the feed or water of healthy poultry, cattle, and swine to promote faster growth and prevent infections.
Tetracycline was patented by Lloyd Conover, which became the most prescribed broad spectrum antibiotic in the United States.
Nystatin was patented and used to cure many disfiguring and disabling fungal infections.
Penicillin resistant strains are one of the most common causes of pneumonia, Streptococcus pneumoniae, as well as many venereal diseases, spread around the world.
SmithKline Beecham patented Amoxicillin or potassium tablets.
Carbapenem antibiotics were originally developed from thienamycin, a naturally derived product of Streptomyces cattleya.
It became difficult to detect new and potentially useful antibiotic classes against the background of known but not useful antibiotics.
SmithKline Beecham first sold the antibiotic in under the tradenames of Amoxicillin, Amoxil, and Trimox.
Streptogramins are effective in the treatment of vancomycin-resistant Staphylococcus.
Oxazolidinones are mainly used as antimicrobials. These antibiotics are considered as a choice of last resort where every other antibiotic therapy has failed.
Out of 89 new medicines emerging on the market, no new antibacterial drugs were approved. Since 1998, only seven new antibacterials have been approved.
Treats or prevents skin infection caused by certain bacteria. This medicine also treats blood infections and certain heart diseases caused by Staphylococcus bacteria.
As bacteria evolve to evade antibiotics, common infections could become deadly. Diseases that were once curable, such as tuberculosis, are becoming harder and more expensive to treat.