The Bubonic Plague started in central Asia, and was spread to the Black Sea area by 1346, via common trade routes. By 1347 it had spread to Sicily through trade routes, and up the Italian peninsula, where it would do the most damage. From Italy the palgue spread to the rest of Europe, but most prominetly in western and central Eruope. The disease was spread from fleas that would bite rats, then the infected rats would spread their disease in a banerial maner to travalers. The expectancy rate of surviving the Bubonic Plague were 50-60%. Side effects included blotty purple skin form internal bleeding, high fever, aching joints, swelling of lymph nodes, and most likely death.