The victim, Kercher, is found in the house she shared with Amanda Knox covered up with her throat slit.
Amanda Knox is joined by her boyfriend, Raffaele Sollecito, when detained by police. Knox suggests her boss, Patrick Lamumba, as a suspect. Lamumba is taken in for interrogation.
Patrick Lamumba is released after his alibi of working at the pub the night of the murder is confirmed. He spent two weeks in prison.
Rudy Guede, a convicted felon for previous robberies, is arrested after investigators find his DNA in a vaginal swab from Kercher. Guede claims that despite having had sexual relations with Kercher, he wasn't the one to murder her.
Amanda Knox, Rudy Guede, and Raffaele Sollecito are officially charged with the murder of Meredith Kercher.
Guede fears a possible alliance between Knox and Sollecito against him.
Guede sentenced to 30 years in prison, later reduced to 16 years after appeals. Knox and Sollecito formally indicted for murder.
Reporters flood the courtroom to get the best media coverage for Italy's trial of the century.
Knox defends herself by claiming she was abused by police interrogators and was under stress and in shock after the murder, causing her strange behavior and forced answers.
The Knox/Sollecito trial wraps up as the final witnesses give their testimony.
American forensic scientists Elizabeth Johnson and Gregory Hampikian start a petition against the credibility of the evidence.
Amanda Knox and Raffaele Sollecito are found guilty by the jury for the stabbing of Meredith Kercher. Knox is sentenced to 26 years while Sollecito is sentenced to 25.
The judge adjourns the hearing to December 11 due to the absence one of the lawyers isn't present.
Knox speaks through tears about being unjustly accused for a crime she and Sollecito simply did not commit.
Experts from La Sapienza University in Rome take the oath and begin to retest the main evidence used against Knox, such as the supposed murder weapon, a kitchen knife previously found with Knox's DNA on the handle, and the clasp of Kercher's bra.
Jury of two judges and six citizens scheduled for Knox's hearing.
A letter Guede wrote about Knox and Sollecito being involved in the murder is brought up by the prosecutor. Knox remains shocked at these accusations.
Forensic specialists find that the DNA evidence against Knox was unsound and highly contaminated during the investigation process. The knife had Knox's DNA as well as Kercher's and Sollecito's, though no blood DNA was found and only skin cell DNA was found. The bra clasp was also taken from the crime scene six weeks after the murder and, though found with Sollecito's and Knox's DNA, contamination was highly likely.
Italian jury overturns murder convictions for Knox and Sollecito. Knox still convicted for defamation for accusing Lamumba. Knox returns to Seattle.
Convictions finally overturned and case closed.