People thought that malaria infected people.
Noticed that malaria could occur near swamps. In Rome, Caesar cleared out swamps to prevent malaria. Malaria is Italian for "bad air".
Joseph Caventou and Pierre Pelletier purify quinine. The quinine molecule is tested on malaria patients and then used as treatment.
Observed malaria infected blood.
Suggested that malaria is transmitted through infected blood.
Identified two species of plasmodium.
Identified plasmodium as the cause of malaria.
Named the female anopheles mosquito as the vector of malaria.
Explained why strains of plasmodium had developed into resistant to treatment drugs.