Hundreds stage protests in Damascus and Aleppo, calling for democratic reforms, demanding for greater civil liberties and freedom for political prisoners after 40 years the Assad autocracy.
4 Killed in the first deaths of the civil war.
Obama says if the Assad regime started using chemical weapons, then the US would 'change its calculus' and intervene.
President Barack Obama calls on Assad to resign and orders Syrian government assets frozen.
Kofi Annan quits as UN-Arab League envoy after his attempts to broker a cease-fire failed.
assault on city of Hama, the epicenter of anti-regime protests, hundreds are left dead by Syrian security forces backed by tanks and snipers.
The United States, Britain, France and Germany and the European Union demand Assad resign, saying he is unfit to lead.
Fighting spreads to Aleppo, Syria's largest city and its former commercial capital. Over time, rebels seize control of about half of the city, but the battle there rages to this day, leaving much of Aleppo in ruins.
—Feb. 4, 2012 — Russia and China veto a resolution in the U.N. Security Council that backs an Arab League plan calling for Assad to step down.
The Syrian National Coalition is created, bringing together the main opposition factions. The umbrella group is hampered from the start by internal division and accusations that its members are out-of-touch exiles
The initial members had defected from Assad's militia.
The Syrian army recaptures the key border town of Qusayr, in an assault led by fighters from Lebanon's Hezbollah
Assad regime accused of killing more than 1,400 people, according to the United States, with chemical weapons in two rebel-held zones near Damascus.
September 2013: Around a dozen rebel groups abandon the Syrian National Coalition and reject its calls for a civil, democratic government. Seven of them later form their own alliance, the Islamic Front, intended to eventually create a state governed by Islamic law.
Syria destroys its chemical weapons production equipment.
February 2014: Two rounds of peace talks led by UN-Arab League mediator Lakhdar Brahimi in Geneva end without a breakthrough.
Brahimi resigns as UN-Arab League envoy to Syria, marking a second failure by the United Nations and Arab League to end the civil war.
09 May 2014: Rebels withdraw part of Homs. This is asymbolic victory for the government, putting the area that had been under siege for more than a year firmly in government hands.
Islamic State group,seizes large parts of northern and western Iraq. In control of around a third of Syria and Iraq, it declares a self-styled Islamic caliphate.
Syrians in government areas vote in presidential elections. Assad, one of three candidates, overwhelmingly wins with 88.7 percent
Islamic State group takes control of Syria's largest oil field, al-Omar, after fierce battles with the Nusra Front, al-Qaida's branch in Syria
Islamic State militants release video of the beheading of American journalist James Foley, the first of five Westerners to be beheaded by the IS group.
Islamic State fighters capture Tabqa military air base in northeastern Syria, eliminating the last government-held outpost in Raqqa province.
IS begins offensive to take Syrian Kurdish town of Kobani, on the Turkish border.
US-led coalition begins airstrikes against Islamic State group targets in Syria
With the help of US-led airstrikes, Kurdish fighters take control of Kobani
IS releases a video of captured Jordanian pilot Muath al-Kaseasbeh being burned to death in a cage, sparking outrage in Jordan, which launches new strikes targeting the militants
IS overruns several Christian villages in Syria's eastern Hassakeh province, taking at least 220 syrian Christians hostage.
IS claims a Jordanian airstrike kills American hostage Kayla Jean Mueller. US officials later confirm her death, but say it wasn't caused by a Jordanian airstrike.