History of mRNA

Main

The idea of “inborn errors of metabolism”

1900 - 1930

Isolation and characterization of DNA and RNA: RNA is different

1930 - 1950

Discovering the relationship between DNA, RNA, and protein production

1951 - 1960

Elucidating the genetic code and the role of mRNA

1961 - 1965

RNA sequencing and structure

1966 - 1975

Splicing of RNA

1976 - 1980

RNA as an enzyme; regulation of transcription and gene expression

1981 - 1989

RNA editing; in vitro evolution; and telomerase

1990 - 1999

Regulatory RNAs; mRNA decay; splicing mutations and disease; the exosome

2000 - 20014